Biology of Disease
The Nature and Investigation of Diseases
1. Nature and Investigation of Diseases
2. Characteristic Features of Diseases
3. Classification of Diseases
4. Epidemiology of Disease
5. Investigating Diseases
6. Types of Pathology Laboratories
7. Role of Hospital Laboratory Tests
8. Hospital Laboratory Tests
9. Evaluation of Laboratory Tests
10. Reference Ranges of Diseases
11. Quality of Test Results and Clinical Auditing
Pathogens and Virulence
1. Pathogens and Virulence: Introduction
2. Types of Pathogens
3. Virulence Factors: Defensive, Offensive
4. Course of Infection
Infectious Diseases and Treatments
1. Infectious Diseases and Treatments: Introduction
2. Infections of the Skin
3. Infections of the Eyes, Ears and Central Nervous System
4. Infections of the Respiratory System
5. Infections of the Gastrointestinal Tract
6. Infections of the Urogenital System
7. Sepsis and Systemic Infections
8. Investigating Infectious Diseases
9. Preventing Infectious Diseases
10. Controlling the Spread of Pathogens
11. Treatment of Infectious Diseases
12. Antiviral Drugs - Treatment of Infectious Diseases
13. Antibacterial Drugs - Treatment of Infectious Diseases
14. Antifungal, Antiprotozoal and Antihelminthic Drugs - Treatment of Infectious Diseases
15. Combination Therapy - Treatment of Infectious Diseases
16. Surgery - Treatment of Infectious Diseases
The Immune System
1. Types of Immune Defense
2. Nonspecific Defenses
3. Specific Immune Responses
4. Small Lymphocytes
5. Production of a Specific Immune Response
Disorders of the Immune System
1. Disorders of the Immune System: Introduction
2. Immunodeficiency Diseases
3. Primary Immunodeficiency Disease
4. Combined T and B deficiencies - Primary Immunodeficiency Disease
5. Antibody deficiencies - Primary Immunodeficiency Disease
6. The DiGeorge anomaly and the Wiskott Aldridge syndrome - Primary Immunodeficiency Disease
7. The Chediak Higashi syndrome - Primary Immunodeficiency Disease
8. Phagocytic defects - Primary Immunodeficiency Disease
9. Complement deficiencies - Primary Immunodeficiency Disease
10. Autoimmune Disorders
11. Classification of Autoimmune Disorders
12. Autoimmune Disorders Affecting Endocrine Glands
13. Antiglomerular Basement Membrane Disease
14. Myasthenia Gravis - Autoimmune Disorders
15. Rheumatoid Arthritis - Autoimmune Disorders
16. Systemic Lupus Erythematosus - Autoimmune Disorders
17. Immunological Hypersensitivity
18. Type I Immunological Hypersensitivity
19. Type II Immunological Hypersensitivity
20. Type III Immunological Hypersensitivity
21. Type IV Delayed Type Immunological Hypersensitivity
Transfusion and Transplantation
1. Transfusion and Transplantation: Introduction
2. Blood and Blood Products for Transfusion
3. The Discovery of the Blood Group Systems
4. The ABO Blood Group System (ISBT 001)
5. The Rh Blood Group System (ISBT 004)
6. Hemolytic Disease of the Newborn
7. Other Blood Group Systems
8. Laboratory Determination of Blood Groups
9. Role of Complement in Transfusion Reactions
10. Hazards of Transfusion
11. Screening of Blood Donors
12. Transplantation of Solid Tissues and Organs
13. HLA System and Typing
14. Immunosuppression
15. Hemopoietic Stem Cell Transplantation
Disorders of the Endocrine System
1. Disorders of the Endocrine System
2. Hormone Production
3. Mechanisms of Hormonal Action
4. Causes of Endocrine Disorders
5. Pituitary Gland
6. Disorders of Pituitary Function
7. Growth Hormone Disorders
8. Diagnosis and Treatment of Growth Hormone Disorders
9. Thyroid Hormone Disorders
10. Diagnosis and Treatment of Thyroid Disorders
11. Regulation of Blood Glucose
12. Diabetes Mellitus
13. Diagnosis and treatment of diabetes mellitus
14. Hypoglycemia - Regulation of Blood Glucose
15. Diagnosis and treatment of hypoglycemia
16. Disorders of the Adrenal Cortex
17. Addison�s Disease - Disorders of the Adrenal Cortex
18. Diagnosis and treatment of Addison�s disease
19. Cushing�s Syndrome - Disorders of the Adrenal Cortex
20. Diagnosis and treatment of Cushing�s syndrome
21. Congenital Adrenal Hyperplasia: Diagnosis and treatment - Disorders of the Adrenal Cortex
22. Conn�s Syndrome: Diagnosis and treatment
23. Reproductive Hormones
24. Disorders of Sex Hormones
Disorders of Water Electrolytes and Urate Balances
1. Disorders of Water, Electrolytes and Urate Balances
2. Kidneys
3. Renal Function Tests
4. Renal Failure: Acute and Chronic renal failure
5. Disorders of Water Homeostasis
6. Disorders of Na+ Homeostasis
7. Disorders of K+ Homeostasis
8. Disorders of Ca2+ Homeostasis
9. Disorders of Phosphate Homeostasis
10. Disorders of Mg2+ Homeostasis
11. Disorders of Urate Metabolism
Disorders of Acid Base Balance
1. Disorders of Acid Base Balance
2. The Production and Transport of Carbon Dioxide
3. Buffering and the Excretion of H+
4. Types of Acid�Base Disorders
5. Metabolic Acid Base Disorders
6. Respiratory Acid Base Disorders
7. Mixed Acid Base Disorders
8. Investigating Acid Base Disorders
Diet and Disease
1. Diet and Disease: Introduction
2. Diet and Nutrition
3. Nutrients and Energy - Diet and Nutrition
4. Carbohydrates - Diet and Nutrition
5. Lipids and fatty acids - Diet and Nutrition
6. Proteins - Diet and Nutrition
7. Water - Diet and Nutrition
8. Vitamins - Diet and Nutrition
9. Minerals and Trace Elements - Diet and Nutrition
10. Protein Energy Malnutrition - Nutritional Disorders
11. Obesity - Nutritional Disorders
12. Anorexia Nervosa and Bulimia Nervosa - Nutritional Disorders
13. Hypovitaminoses and Hypervitaminoses - Disorders of Vitamin Nutrition
14. Nutritional Disorders of Minerals and Trace Elements
15. Investigating Nutritional Disorders
16. Protein-Energy Malnutrition - Investigating Nutritional Disorders
17. Obesity, Anorexia Nervosa and Bulimia Nervosa - Investigating Nutritional Disorders
18. Vitamins - Investigating Nutritional Disorders
19. Minerals and Trace Elements - Investigating Nutritional Disorders
20. General Management of Nutritional Disorders
Disorders of the Gastrointestinal Tract Pancreas Liver and Gall Bladder
1. Gastrointestinal Tract and its Accessory Organs
2. Digestion: Mouth, Stomach, Small Intestine
3. Absorption of the Products of Digestion
4. Activities of the Large Intestine
5. Small Intestine and Homeostasis
6. Hormonal Control of GIT Secretions
7. Disorders of the Exocrine Pancreas
8. Disorders of the Liver, Gall Bladder and Bile Duct
9. Disorders of the Stomach
10. Disorders of the Small Intestine
11. Disorders of the Large Intestine
Toxicology
1. Toxicology
2. Drug Action, Metabolism, Distribution and Excretion
3. Physiological Detoxification Mechanisms
4. Symptomatic Poisoning
5. Paracetamol - Toxicology Poisons
6. Aspirin - Toxicology Poisons
7. Ethanol - Toxicology Poisons
8. Methanol - Toxicology Poisons
9. Ethylene Glycol - Toxicology Poisons
10. Barbiturates - Toxicology Poisons
11. Carbon Monoxide - Toxicology Poisons
12. Paraquat - Toxicology Poisons
13. Metals - Toxicology Poisons
Disorders of the Blood
1. Disorders of the Blood
2. Blood Cells and Platelets
3. Hemoglobins
4. Hemostasis and Blood Clotting
5. Anemias: Microcytic and Macrocytic Anemia
6. Microcytic Anemias
7. Macrocytic Anemia
8. Hemoglobinopathies
9. Sickle Cell Anemia - Hemoglobinopathies
10. Thalassemias - Hemoglobinopathies
11. Glucose 6-Phosphate Dehydrogenase Deficiency (G6PD) Favism
12. Clinical Aspects of Clotting
13. Thrombocytopenia and Thrombocytosis
Disorders of the Cardiovascular System
1. Disorders of the Cardiovascular System: Introduction
2. Heart and Circulatory Systems
3. Blood Vessels
4. Blood Pressure
5. Investigating Cardiac Function in Health and Disease
6. Electrocardiogram (ECG) - Investigating Cardiac Function in Health and Disease
7. Endocarditis
8. Abnormal Heart Rhythms
9. Cardic Failure: Investigation, Treatment, Chronic and Acute Heart Failure
10. Ischemic Heart Disease
11. Cardiomyopathies
12. Heart Valve Disorders
13. Heart Tumors
14. Atherosclerosis or Arteriosclerosis
15. Angina - Atherosclerosis or Arteriosclerosis
16. Cholesterol and Lipoproteins
17. Myocardial Infarction
18. Pericardial Diseases
19. Disorders of Arteries and Veins
20. Clinical Problems Associated with Blood Pressure
Genetic Diseases
1. Genetic Diseases
2. Genetics and DNA
3. DNA Replication and the Cell Cycle
4. Genotype and Phenotype
5. Inheritance and Mutations
6. Sex linked Genetic Diseases
7. Inherited Gene Disorders
8. Consequences of an Enzyme Deficiency
9. National Screening Programs for Inherited Diseases
10. Chromosomes and the Human Karyotype
11. Fragile Sites - Chromosomes and the Human Karyotype
12. Chromosomal Mutations or Aberrations
13. Aneuploidy - Variations in Chromosome Numbers
14. Euploidy - Variations in Chromosome Numbers
15. Detecting, Diagnosing and Screening Human Genetics Diseases
Membrane Organelle and Cytoskeletal Disorders
1. Nucleus and Nucleocytoplasmic Transport
2. Plasma Membrane Disorders
3. Cystic Fibrosis: Diagnosis and treatment - Plasma Membrane Disorders
4. Mitochondrial Disorders: Causes, Diagnosis and Treatment
5. Causes of Mitochondrial Disorders
6. Diagnosis and Treatment of Mitochondrial Disorders
7. Peroxisomal Disorders
8. Diagnosis and Treatment of Peroxisomal Disorders
9. Lysosomal Disorders
10. Diagnosis and Treatment of Lysosomal Storage Disorders
11. Cytoskeletal Disorders
12. Muscular Dystrophies: Diagnosis and treatment
13. Hereditary Elliptocytosis and Spherocytosis: Diagnosis and treatment
Cancer
1. Cancer
2. Classification of Cancer Types
3. Epidemiology of Cancer
4. Molecular Biology of Cancer
5. Causes of Cancer
6. Clinical Tests for Cancer - General Diagnosis of Cancer
7. General Treatment of Cancer
8. Chemotherapy - General Treatment of Cancer
9. Radiation Therapy - General Treatment of Cancer
10. Immunotherapy - General Treatment of Cancer
11. Lung Cancer: Classification, Treatment, Signs, symptoms, diagnosis and staging
12. Breast Cancer: Treatment, Signs, symptoms, diagnosis and staging
13. Prostate Cancer: Treatment, Signs, symptoms and staging
14. Colorectal Cancer: Treatment, Signs, symptoms, diagnosis and staging
15. Leukemias: Chronic myelogenous, Acute myeloid, Acute lymphoblastic leukemia
Aging and Disease
1. Aging and Disease
2. Aging of Cells, Tissues, Organs and Systems
3. Causes of Aging: Wear and Tear, Genome Based Theories
4. Age Related Diseases
5. Calorie Restriction and Aging
6. Investigations and Management of the Elderly
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