Pharmaceutical Industrial Management - Pharmacy Department
PART I: INTRDUCTORY CHAPTERS
Chapter 1: Drug discovery
1. Drug discovery - Elements, Sources
2. Collaborating disciplines - Drug discovery | Pharmaceutical
3. Small - versus large-molecule paradigms - Drug discovery | Pharmaceutical
4. Contemporary drug discovery case studies - Drug discovery | Pharmaceutical
5. Summary and outlook to the future - Drug discovery | Pharmaceutical
6. Review questions and answers - Drug discovery | Pharmaceutical
Chapter 2: Drug development
1. Drug development - Pharmaceutical
2. Stage-gate process of new drug discovery and development - Pharmaceutical
3. Pharmaceutical development - Drug development | Pharmaceutical
4. Regulatory approval - Drug development | Pharmaceutical
5. Postcommercialization activities - Drug development | Pharmaceutical
6. Review questions and answers - Drug development | Pharmaceutical
Chapter 3: Pharmaceutical considerations
1. Pharmaceutical considerations - Pharmaceutical
2. Advantages of pharmaceutical dosage forms - Pharmaceutical
3. Influential factors in dosage form design - Pharmaceutical
4. Review questions and answers - Pharmaceutical considerations
Chapter 4: Biopharmaceutical considerations
1. Biopharmaceutical considerations - Pharmaceutical
2. Diffusion: Drug transport across a polymeric barrier - Biopharmaceutical
3. Principles of diffusion - Biopharmaceutical
4. Diffusion rate - Biopharmaceutical
5. Dissolution - Biopharmaceutical
6. Absorption - Biopharmaceutical
7. Review questions and answers - Biopharmaceutical considerations
Chapter 5: Pharmacy math and statistics
1. Pharmacy math and statistics - Pharmaceutical
2. Systems of measure - Pharmacy math and statistics | Pharmaceutical
3. Ratio and proportion - Pharmacy math and statistics | Pharmaceutical
4. Concentration calculations - Pharmacy math and statistics | Pharmaceutical
5. Clinical dose calculations - Pharmacy math and statistics | Pharmaceutical
6. Statistical measures - Pharmacy math and statistics | Pharmaceutical
7. Tests of statistical significance - Pharmacy math and statistics | Pharmaceutical
8. Review questions and answers - Pharmacy math and statistics | Pharmaceutical
PART II: PHYSICOCHEMICAL PRINCIPLES
Chapter 6: Complexation and protein binding
1. Complexation and protein binding - Pharmaceutical
2. Types of complexes - Pharmaceutical
3. Protein binding - Pharmaceutical
4. Review questions answers - Complexation and protein binding | Pharmaceutical
Chapter 7: Chemical kinetics and stability
1. Chemical kinetics and stability - Pharmaceutical
2. Reaction rate and order - Pharmaceutical
3. Factors affecting reaction kinetics - Pharmaceutical
4. Drug degradation pathways - Pharmaceutical
5. Stabilization strategies - Pharmaceutical
6. Review questions answers - Chemical kinetics and stability | Pharmaceutical
Chapter 8: Interfacial phenomena
1. Interfacial phenomena - Pharmaceutical
2. Liquid–liquid and liquid-gas interfaces - Interfacial phenomena | Pharmaceutical
3. Solid-gas interface: Adsorption - Pharmaceutical
4. Solid-Liquid interface - Pharmaceutical
5. Biological and pharmaceutical applications
6. Review questions answers - Interfacial phenomena | Pharmaceutical
Chapter 9: Colloidal dispersions
1. Colloidal dispersions - Pharmaceutical
2. Types of colloidal systems - Pharmaceutical
3. Preparation of colloidal solutions - Pharmaceutical
4. Properties of colloidal solutions - Kinetic, Electrical, Colligative, Optical properties
5. Physical stability of colloids - Pharmaceutical
6. Review questions answers - Colloidal dispersions | Pharmaceutical
Chapter 10: Surfactants and micelles
1. Surfactants and micelles - Pharmaceutical
2. Surfactants - Pharmaceutical
3. Types of surfactants - Pharmaceutical
4. Hydrophile-lipophile balance system - Surfactants | Pharmaceutical
5. Micelles - Pharmaceutical
6. Factors affecting critical micelle concentration and micellar size - Pharmaceutical
7. Micellar solubilization - Pharmaceutical
8. Review questions answers - Surfactants and micelles | Pharmaceutical
Chapter 11: Pharmaceutical polymers
1. Pharmaceutical polymers
2. Definitions and architectures of polymers - Pharmaceutical polymers
3. Polymer molecular weight and weight distribution - Pharmaceutical polymers
4. Biodegradablity and biocompatibility - Pharmaceutical polymers
5. Physicochemical properties and solubility - Pharmaceutical polymers
6. Block copolymers - Pharmaceutical polymers
7. Intelligent or stimuli-sensitive polymers - Pharmaceutical polymers
8. Water-soluble polymers - Pharmaceutical polymers
9. Bioadhesive/mucoadhesive polymers - Pharmaceutical polymers
10. Review questions answers - Pharmaceutical polymers
Chapter 12: Rheology
1. Rheology - Pharmaceutical
2. Newtonian flow - Rheology | Pharmaceutical
3. Non-Newtonian flow - Rheology | Pharmaceutical
4. Thixotropy - Rheology | Pharmaceutical
5. Pharmaceutical applications of rheology
6. Review questions answers - Rheology | Pharmaceutical
Chapter 13: Radiopharmaceuticals
1. Radiopharmaceuticals - Pharmaceutical
2. Biomedical applications of radiopharmaceuticals - Pharmaceutical
3. Radiation detection equipment - Radiopharmaceuticals
4. Formulation of radiopharmaceuticals
5. Calculations of Radiopharmaceuticals
6. Review questions answers - Radiopharmaceuticals
Chapter 14: Drug delivery systems
1. Drug delivery systems - Pharmaceutical
2. Targeted drug delivery - Pharmaceutical
3. Prodrugs - Drug delivery systems | Pharmaceutical
4. Soluble macromolecular carriers - Drug delivery systems | Pharmaceutical
5. Particulate carrier systems - Drug delivery systems | Pharmaceutical
6. Oral drug delivery - Drug delivery systems | Pharmaceutical
7. Alternative routes of delivery - Drug delivery systems | Pharmaceutical
8. Review questions answers - Drug delivery systems | Pharmaceutical
Chapter 15: Organ-specific drug delivery
1. Organ-specific drug delivery - Pharmaceutical
2. Need for alternate, nonoral routes to the systemic circulation - Organ-specific drug delivery | Pharmaceutical
3. Need for organ specific and targeted drug delivery - Organ-specific drug delivery | Pharmaceutical
4. Local drug delivery to the lung - Organ-specific drug delivery | Pharmaceutical
5. Systemic drug delivery through the lung - Organ-specific drug delivery | Pharmaceutical
6. Devices for pulmonary drug delivery - Organ-specific drug delivery | Pharmaceutical
7. Ocular drug delivery - Organ-specific drug delivery | Pharmaceutical
8. Brain targeted drug delivery - Organ-specific drug delivery | Pharmaceutical
9. Liver-targeted drug delivery - Organ-specific drug delivery | Pharmaceutical
10. Colon-targeted drug delivery - Organ-specific drug delivery | Pharmaceutical
11. Combination and other strategies for colon targeting - Organ-specific drug delivery | Pharmaceutical
12. Review questions answers - Organ-specific drug delivery | Pharmaceutical
PART III: DOSAGE FORMS
Chapter 16: Suspensions
1. Suspensions - Dosage forms | Pharmaceutical
2. Types of suspensions - Dosage forms | Pharmaceutical
3. Powder for suspension - Dosage forms | Pharmaceutical
4. Quality attributes - Dosage forms | Pharmaceutical
5. Formulation considerations - Dosage forms | Pharmaceutical
6. Manufacturing process - Dosage forms | Pharmaceutical
7. Review questions answers - Suspensions | Dosage forms | Pharmaceutical
Chapter 17: Emulsions
1. Emulsions - Dosage forms | Pharmaceutical
2. Types of emulsions - Dosage forms | Pharmaceutical
3. Quality attributes - Emulsions | Dosage forms | Pharmaceutical
4. Formulation considerations - Emulsions | Dosage forms | Pharmaceutical
5. Emulsification - Dosage forms | Pharmaceutical
6. Manufacturing process - Emulsions | Dosage forms | Pharmaceutical
7. Stability - Emulsions | Dosage forms | Pharmaceutical
8. Review questions answers - Emulsions | Dosage forms | Pharmaceutical
Chapter 18: Pharmaceutical solutions
1. Pharmaceutical solutions
2. Types of solutions - Pharmaceutical
3. Quality attributes - Pharmaceutical solutions
4. Formulation components and manufacturing process - Pharmaceutical solutions
5. Solubility - Pharmaceutical solutions
6. Stability - Pharmaceutical solutions
7. Review questions answers - Pharmaceutical solutions
Chapter 19: Powders and granules
1. Powders and granules - Pharmaceutical
2. Production of powders and granules - Pharmaceutical
3. Analyses of powders - Pharmaceutical
4. Particle shape and size - Analyses of powders - Pharmaceutical
5. Surface area - Analyses of powders - Pharmaceutical
6. Density and porosity - Analyses of powders - Pharmaceutical
7. Flow - Analyses of powders - Pharmaceutical
8. Compactibility - Analyses of powders - Pharmaceutical
9. Content uniformity - Analyses of powders - Pharmaceutical
10. Powder processing - Pharmaceutical
11. Powders as dosage forms - Pharmaceutical
12. Review questions answers - Pharmaceutical
Chapter 20: Tablets
1. Tablets - Pharmaceutical
2. Types of tablets - Pharmaceutical
3. Tablet formulation - Pharmaceutical
4. Manufacturing of tablets - Pharmaceutical
5. Evaluation of tablets - Pharmaceutical
6. Relationship among disintegration, dissolution, and absorption - Tablets | Pharmaceutical
7. Review questions answers - Tablets | Pharmaceutical
Chapter 21: Capsules
1. Capsules - Pharmaceutical
2. Hard gelatin capsules - Pharmaceutical
3. Soft gelatin capsules - Pharmaceutical
4. Evaluation of capsule drug products - Pharmaceutical
5. Shelf-life tests - Capsules | Pharmaceutical
6. Review questions answers - Capsules | Pharmaceutical
Chapter 22: Parenteral drug products
1. Parenteral drug products - Pharmaceutical
2. Parenteral routes of administration - Parenteral drug products | Pharmaceutical
3. Types of parenteral dosage forms - Pharmaceutical
4. Quality attributes and evaluation - Parenteral drug products | Pharmaceutical
5. Formulation components - Parenteral drug products | Pharmaceutical
6. Sterilization - Parenteral drug products | Pharmaceutical
7. Review questions answers - Parenteral drug products | Pharmaceutical
Chapter 23: Semisolid dosage forms
1. Semisolid dosage forms - Pharmaceutical
2. Ointments and Types of ointment bases - Pharmaceutical
3. Creams - Pharmaceutical
4. Gels and jellies - Pharmaceutical
5. Lotions - Pharmaceutical
6. Pastes - Pharmaceutical
7. Foams - Pharmaceutical
8. Manufacturing processes - Semisolid dosage forms | Pharmaceutical
9. Analysis of semisolid dosage forms - Pharmaceutical
10. Review questions answers - Semisolid dosage forms | Pharmaceutical
Chapter 24: Inserts, implants, and devices
1. Inserts, implants, and devices - Pharmaceutical
2. Ocular inserts, Suppositories, Vaginal rings - Pharmaceutical
3. Implants and Types of implants - Pharmaceutical
4. Devices - Pharmaceutical
5. Review questions answers - Pharmaceutical
Chapter 25: Protein and peptide drug delivery
1. Protein and peptide drug delivery - Pharmaceutical
2. Structure of Proteins and peptides - Amino acids | Pharmaceutical
3. Types of protein and peptide therapeutics - Pharmaceutical
4. Protein characterization - Pharmaceutical
5. Instability - Protein and peptide drug delivery | Pharmaceutical
6. Antigenicity and immunogenicity - Protein and peptide drug delivery | Pharmaceutical
7. Drug product formulation and process - Protein and peptide drug delivery | Pharmaceutical
8. Review questions answers - Protein and peptide drug delivery | Pharmaceutical
Chapter 26: Biotechnology-based drugs
1. Biotechnology-based drugs - Pharmaceutical
2. Gene and gene expression - Biotechnology-based drugs | Pharmaceutical
3. Gene silencing - Biotechnology-based drugs | Pharmaceutical
4. Gene silencing technologies - Biotechnology-based drugs | Pharmaceutical
5. Gene therapy - Pharmaceutical
6. Review questions answers - Biotechnology-based drugs | Pharmaceutical
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