Pharmaceutical Microbiology - Pharmacy Department
Chapter 1: Introduction and Scope
1. Scope of Pharmaceutical Microbiology
2. Historical Development and Milestones of Microbiology - Pharmaceutical Microbiology
Chapter 2: Structure and Function of Bacterial Cells
1. Introduction - Bacterial Cells
2. Characteristic Features of bacteria
3. Predominant activities of bacteria
4. Organization of Microbial Cells
5. Types of Microbial Cells
6. Archaeobacteria and Eubacteria - Pharmaceutical Microbiology
7. Structure and Function of Bacterial Cells
8. Typical Bacterial Cell - Structure and Function of Bacterial Cells
9. Capsules and Slimes - Structure and Function of Bacterial Cells
10. Flagella and Fimbria - Salient Features, Structure and Function of Bacterial Cells
11. Cell Envelope - Structure and Function of Bacterial Cells
12. Gram-Positive and Gram-Negative Bacteria - Structure and Function of Bacterial Cells
13. Significance of Teichoic Acids - Salient Features, Structure and Function of Bacterial Cells
14. The Cell Membrane - Structure and Function of Bacterial Cells
15. Bacterial Cytoplasm - Structure and Function of Bacterial Cells
16. Ribosomes - Characteristic Features, Structure and Function of Bacterial Cells
17. Cellular Reserve Materials - Structure and Function of Bacterial Cells
Chapter 3: Characterization, Classification and Taxonomy of Microbes
1. Introduction - Characterization, Classification and Taxonomy of Microbes
2. Characterization of Microbes
3. Classification of Microbes or Microorganisms
4. Difficulties Encountered in Classification of Microorganisms
5. Objectives of Classification of Microbes
6. Genetic Methods of Classifying Microbes - Genetic relatedness, Intuitive method, Numerical taxonomy
7. Systematized Classification of Microbes or Microorganisms
8. Taxonomy of Microbes or Microorganisms
9. The Kingdom Prokaryotae - Pharmaceutical Microbiology
10. Actinomycetes - General Characteristics, Significance, Classification | The Kingdom Prokaryotae
11. Actinomycetes and Related Organisms - Group, Genus, Order, Family, Salient Features | The Kingdom Prokaryotae
12. Bacteria [Plural of ‘Bacterium’] - Salient Features, Size and Shape, Structure | The Kingdom Prokaryotae | Pharmaceutical Microbiology
13. Rickettsia and Coxiella - Salient Features, Examples | The Kingdom Prokaryotae | Pharmaceutical Microbiology
14. Spirochaetes - Salient Features | The Kingdom Prokaryotae | Pharmaceutical Microbiology
Chapter 4: Identification of Microorganisms
1. Introduction - Identification of Microorganisms | Pharmaceutical Microbiology
2. Morphology - Identification of Microorganisms | Pharmaceutical Microbiology
3. Selective and Diagnostic Media - Identification of Microorganisms | Pharmaceutical Microbiology
4. Cultural Characteristics - Identification of Microorganisms | Pharmaceutical Microbiology
5. Biochemical Tests (or Properties) - Identification of Microorganisms | Pharmaceutical Microbiology
6. Profile of Microbial Stains - Identification of Microorganisms | Pharmaceutical Microbiology
7. Preparation of Bacterial Specimens for Light Microscopy - Profile of Microbial Stains | Identification of Microorganisms | Pharmaceutical Microbiology
8. Microscopy : The Different Instruments - Concepts, Variants, Types, Diagram, Methodology | Profile of Microbial Stains | Identification of Microorganisms | Pharmaceutical Microbiology
9. Concepts of Microscopy - Identification of Microorganisms | Pharmaceutical Microbiology
10. Microscope Variants - Salient Features, Methodology, Examples, Applications, Diagram | Identification of Microorganisms | Pharmaceutical Microbiology
11. Types of Electron Microscopes - Concepts, Diagram, Methodology | Pharmaceutical Microbiology
Chapter 5: Nutrition, Cultivation and Isolation of microorganisms : Bacteria-Actinomycetes-Fungi-Viruses
1. Introduction - Nutrition, Cultivation and Isolation of microorganisms | Pharmaceutical Microbiology
2. Nutrition, Cultivation and Isolation of Bacteria - Pharmaceutical Microbiology
3. Nutrition, Cultivation and Isolation of Actinomycetes - Pharmaceutical Microbiology
4. Nutrition, Cultivation, Reproduction and Isolation of Fungi - Nutrition, Cultivation and Isolation of microorganisms | Pharmaceutical Microbiology
5. Industrial Importance of Fungi - Pharmaceutical Microbiology
6. Nutrition, Cultivation and Isolation of Viruses - Nutrition, Cultivation and Isolation of microorganisms | Pharmaceutical Microbiology
Chapter 6: Microbial Genetics and Variations
1. Microbial Genetics and Variations - Example, Advantages
2. Microbial Genetics - Pharmaceutical Microbiology
3. Structure and Function of Genetic Material - Microbial Genetics | Pharmaceutical Microbiology
4. Genotype and Phenotype - Microbial Genetics | Pharmaceutical Microbiology
5. Adaptation and Mutation - Microbial Genetics | Pharmaceutical Microbiology
6. DNA and Chromosomes - Microbial Genetics | Pharmaceutical Microbiology
7. DNA Replication - Microbial Genetics | Pharmaceutical Microbiology
8. Rate of DNA Replication - Microbial Genetics | Pharmaceutical Microbiology
9. Flow of Genetic Information - Microbial Genetics | Pharmaceutical Microbiology
10. Bacterial Transformation - Microbial Genetics | Pharmaceutical Microbiology
11. Bacterial Transcription - Microbial Genetics | Pharmaceutical Microbiology
12. Bacterial Translation - Microbial Genetics | Pharmaceutical Microbiology
13. Bacterial Conjugation - Microbial Genetics | Pharmaceutical Microbiology
14. Bacterial Transduction - Microbial Genetics | Pharmaceutical Microbiology
15. Bacterial Transfection - Microbial Genetics | Pharmaceutical Microbiology
16. Microbial Phage Conversion - Microbial Genetics | Pharmaceutical Microbiology
17. Microbial Variations [Genetic Manipulation in Microorganisms] - Pharmaceutical Microbiology
Chapter 7: Microbial Control by Physical and Chemical Methods
1. Introduction - Microbial Control by Physical and Chemical Methods | Pharmaceutical Microbiology
2. Microbial Control by Physical Methods - Pharmaceutical Microbiology
3. Microbial Control by Chemical Methods - Pharmaceutical Microbiology
4. Experimental Parameters Influencing the Antimicrobial Agent Activity - Pharmaceutical Microbiology
Chapter 8: Sterility Testing: Pharmaceutical Products
1. Sterility Testing: Pharmaceutical Products
2. Methods of Sterility Testing: Pharmaceutical Products - Pharmaceutical Microbiology
3. Sampling: Probability Profile - Sterility Testing: Pharmaceutical Products
4. Overall Conclusions - Sterility Testing: Pharmaceutical Products
Chapter 9: Immune Systems
1. Immune Systems - Introduction
2. Types of Specific Immunity - Pharmaceutical Microbiology
3. Duality of Immune System - Pharmaceutical Microbiology
4. Immunological Memory - Pharmaceutical Microbiology
5. Natural Resistance and Nonspecific Defense Mechanisms [or Defensive Mechanisms of Body] - Pharmaceutical Microbiology
Chapter 10: Microbiological (Microbial) Assays: Antibiotics-Vitamins- Amino Acids
1. Microbiological (Microbial) Assays: Antibiotics-Vitamins- Amino Acids - Importance and Usefulness, Principle, Methodologies | Pharmaceutical Microbiology
2. Variants In Assay Profile - Microbiological (Microbial) Assays | Pharmaceutical Microbiology
3. Types of Microbiological (Microbial) Assays - Pharmaceutical Microbiology
4. Radioenzymatic [Transferase] Assays - Microbiological (Microbial) Assays | Pharmaceutical Microbiology
5. Analytical Methods For Microbial Assays - Pharmaceutical Microbiology
6. Antibiotics Assays - Examples of Pharmaceutical Microbial Assays - Pharmaceutical Microbiology
7. Assay of Antibiotics by Turbidimetric (or Nephelometric) Methods - Pharmaceutical Microbiology
Glossary
1. Pharmaceutical Microbiology: Glossary, Technical Words, Terms
2. Pharmaceutical Microbiology: Glossary, Technical Words, Terms
3. Pharmaceutical Microbiology: Glossary, Technical Words, Terms
Part 1 - Biology of microorganisms
Chapter 1: Introduction to pharmaceutical microbiology
1. Introduction to pharmaceutical microbiology -
Chapter 2: Fundamental features of microbiology
1. Fundamental features of microbiology - Introduction
2. Naming of microorganisms - Fundamental features of microbiology
3. Microbial metabolism - Fundamental features of microbiology
4. Microbial cultivation - Fundamental features of microbiology
5. Culture media - Fundamental features of microbiology
6. Cultivation methods - Microbial Cultivation - Fundamental features of microbiology
7. Planktonic and sessile (biofilm) growth - Fundamental features of microbiology
8. Enumeration of microorganisms - Fundamental features of microbiology
9. Microbial genetics - Fundamental features of microbiology
10. Bacteria - Microbial Genetics - Fundamental features of microbiology
11. Eukaryotes - Microbial Genetics - Fundamental features of microbiology
12. Genetic Variation and Gene Expression - Microbial Genetics - Fundamental features of microbiology
13. Pharmaceutical Importance of the Major Categories of Microorganisms - Microbiology
14. Preservation of Microorganisms - Fundamental features of microbiology
Chapter 3: Bacteria
1. Bacteria - Pharmaceutical Microbiology
2. Bacterial Ultrastructure - Bacteria
3. Cellular Components - Bacterial Ultrastructure - Bacteria
4. Cell Wall - Bacteria
5. Biofilms - Bacteria
6. Bacterial sporulation - Bacteria
7. Bacterial Ultrastructure - Bacteria
8. Bacterial Reproduction and Growth Kinetics - Bacteria
9. Population Growth of Bacteria - Bacteria
10. Bacterial Growth on Different Media - Bacteria
11. Growth and Genetic Exchange of Bacteria - Bacteria
12. Transformation - Bacterial Reproduction - Bacteria
13. Transduction - Bacterial Reproduction - Bacteria
14. Conjugation - Bacterial Reproduction - Bacteria
15. Environmental Factors that Influence Growth and Survival of Bacteria - Bacteria
16. Physicochemical Factors that affect Growth and Survival of Bacteria - Bacteria
17. Nutrition and Growth - Factors Affecting the Growth of Bacteria - Bacteria
18. Detection, Identification and Characterization of Organisms of Pharmaceutical and Medical Significance - Bacteria
19. Culture Techniques - Bacteria - Microbiology
20. Culture Techniques - Types - Bacteria
21. Microscopy of Organisms of Pharmaceutical and Medical Significance - Bacteria
22. Biochemical Testing and Rapid Identification of Organisms of Pharmaceutical and Medical Significance - Bacteria
23. Molecular Approaches to Identification of Bacterial Species - Pharmaceutical Microbiology
24. Pharmaceutically and Medically Relevant Microorganisms - Bacteria | Pharmaceutical Microbiology
Chapter 4: Fungi
1. Fungi - What are fungi? | Pharmaceutical Microbiology
2. Structure of the Fungal Cell - Microbiology
3. Medical significance of fungi - Microbiology
4. Antifungal Therapy - Pharmaceutical Microbiology
5. Medically Important Fungal Pathogens of Humans - Pharmaceutical Microbiology
6. Emerging Fungal Pathogens - Pharmaceutical Microbiology
7. Antibiotic Production By Fungi - Pharmaceutical Microbiology
Chapter 5: Viruses
1. Viruses - Pharmaceutical Microbiology
2. General Structure of Viruses - Viruses
3. Virus-Host Cell Interactions - Pharmaceutical Microbiology
4. HIV - Virus-Host Cell Interactions - Pharmaceutical Microbiology
5. Tumour Viruses - Virus-Host Cell Interactions - Pharmaceutical Microbiology
6. Multiplication of Human Viruses - Pharmaceutical Microbiology
7. Cultivation of Human Viruses - Pharmaceutical Microbiology
8. Cell Culture - Types of Cultivation of Human Viruses - Pharmaceutical Microbiology
9. The Chick Embryo - Types of Cultivation of Human Viruses - Pharmaceutical Microbiology
10. Animal Inoculation - Types of Cultivation of Human Viruses - Pharmaceutical Microbiology
11. Antiviral chemotherapy- Control of Viruses - Pharmaceutical Microbiology
12. Vaccination - Viruses | Pharmaceutical Microbiology
13. Viricidal Effects of Chemical and Physical Agents on Viruses - Pharmaceutical Microbiology
14. Control of Viruses in Pharmaceutical Products - Pharmaceutical Microbiology
15. Viruses and Gene Therapy - Pharmaceutical Microbiology
16. Bacteriophages - Viruses as Antimicrobials - Pharmaceutical Microbiology
17. Use of Bacteriophages to Treat Bacterial Infection - Pharmaceutical Microbiology
18. Epidemiological Uses and Diagnosis - Viruses - Pharmaceutical Microbiology
19. Prions - Viruses | Pharmaceutical Microbiology
Chapter 6: Protozoa
1. Protozoa - Parasitism, Habitats
2. Physiology of Parasitic Protozoa - Pharmaceutical Microbiology
3. Blood and Tissue Parasites - Protozoa
4. Malaria - Protozoa | Pharmaceutical Microbiology
5. Life Cycle of Plasmodia (Malarial causative) - Protozoa | Pharmaceutical Microbiology
6. Trypanosomatids - Protozoa | Pharmaceutical Microbiology
7. American Trypanosomiasis (Chagas Disease) - Protozoa | Pharmaceutical Microbiology
8. African Trypanosomiasis (Sleeping Sickness) - Protozoa | Pharmaceutical Microbiology
9. Cutaneous and mucocutaneous leishmaniasis - Protozoa | Pharmaceutical Microbiology
10. Visceral Leishmaniasis ( Kala Azar) - Protozoa | Pharmaceutical Microbiology
11. Toxoplasma Gondii - Protozoa | Pharmaceutical Microbiology
12. Intestinal Parasites - Protozoa | Pharmaceutical Microbiology
13. Giardia lamblia (syn. intestinalis, duodenalis) - Intestinal Parasites - Protozoa | Pharmaceutical Microbiology
14. Entamoeba histolytica - Intestinal Parasites - Protozoa | Pharmaceutical Microbiology
15. Cryptosporidium parvum - Intestinal Parasites - Protozoa | Pharmaceutical Microbiology
16. Trichomonas and Free living Amoebas - Protozoa | Pharmaceutical Microbiology
17. Host response to infection - Protozoa | Pharmaceutical Microbiology
18. Immune Response - Host Response to Infection - Protozoa | Pharmaceutical Microbiology
19. Immune Pathology - Host Response to Infection - Protozoa | Pharmaceutical Microbiology
20. Immune Evasion - Host Response to Infection - Protozoa | Pharmaceutical Microbiology
21. Detection of Parasites - Protozoa | Pharmaceutical Microbiology
22. Methods of detection of Parasites - Protozoa | Pharmaceutical Microbiology
23. Antibody Based Technologies - Methods of Detection of Parasites - Protozoa | Pharmaceutical Microbiology
24. DNA Based Technologies - Methods of Detection of Parasites - Protozoa | Pharmaceutical Microbiology
25. Alternative Methods - Methods of Detection of Parasites - Protozoa | Pharmaceutical Microbiology
26. Analysis of Samples - Protozoa | Pharmaceutical Microbiology
27. Control of Protozoan Parasites - Protozoa | Pharmaceutical Microbiology
28. Chemotherapy - Control of Protozoan Parasites - Protozoa | Pharmaceutical Microbiology
29. Other Approaches to Control - Control of Protozoan Parasites - Protozoa | Pharmaceutical Microbiology
Part 2 - Pathogens and host responses
Chapter 7: Principles Of Microbial Pathogenicity And Epidemiology
1. Principles of Microbial Pathogenicity and Epidemiology - Pharmaceutical Microbiology
2. The Human Microbiome - Microbial Pathogenicity and Epidemiology | Pharmaceutical Microbiology
3. Skin - Portals of Entry - Microbial Pathogenicity and Epidemiology | Pharmaceutical Microbiology
4. Consolidation - Microbial Pathogenicity and Epidemiology | Pharmaceutical Microbiology
5. Nutrient Acquisition - Consolidation - Microbial Pathogenicity and Epidemiology | Pharmaceutical Microbiology
6. Biofilms - Consolidation - Microbial Pathogenicity and Epidemiology | Pharmaceutical Microbiology
7. Resistance to Host Defences - Consolidation - Microbial Pathogenicity and Epidemiology | Pharmaceutical Microbiology
8. Manifestation of Disease - Microbial Pathogenicity and Epidemiology | Pharmaceutical Microbiology
9. Damage to Tissues - Microbial Pathogenicity and Epidemiology | Pharmaceutical Microbiology
10. Recovery From Infection: Exit of Microorganisms - Microbial Pathogenicity and Epidemiology | Pharmaceutical Microbiology
11. Epidemiology of Infectious Disease - Microbial Pathogenicity and Epidemiology | Pharmaceutical Microbiology
Chapter 8: Microbial Biofilms: Consequences For Health
1. Microbial Biofilms: Consequences For Health - Pharmaceutical Microbiology
2. Biofilms - Microbial Biofilms | Pharmaceutical Microbiology
3. Biofilms in Nature and the Consequences to Health - Microbial Biofilms | Pharmaceutical Microbiology
4. Biofilms in the Food Industry - Microbial Biofilms | Pharmaceutical Microbiology
5. Biofilms in Hospitals - Microbial Biofilms | Pharmaceutical Microbiology
6. Biofilms and Medical Devices - Microbial Biofilms | Pharmaceutical Microbiology
7. Tolerance of Biofilms to Antimicrobials - Microbial Biofilms | Pharmaceutical Microbiology
8. Mechanisms of Biofilm Tolerance - Microbial Biofilms | Pharmaceutical Microbiology
9. Treatment of Chronic Biofilm Infections - Microbial Biofilms | Pharmaceutical Microbiology
10. A New Biofilm Assay - Microbial Biofilms | Pharmaceutical Microbiology
11. Better Use of Existing Antimicrobials - Microbial Biofilms | Pharmaceutical Microbiology
12. Next-Generation Antimicrobials - Microbial Biofilms | Pharmaceutical Microbiology
13. Conceptual Evaluation of Antibiotics - Microbial Biofilms | Pharmaceutical Microbiology
14. Biofilm Assays - Microbial Biofilms | Pharmaceutical Microbiology
Chapter 9: Immunology
1. Immunology - Pharmaceutical Microbiology
2. Immunology - Immunology, Immune System, Scope Of Immunology
3. Definitions and Outline Structure of the Immune System - Immunology
4. Cells of the Immune System - Immunology
5. The Innate Immune System - Immunology
6. The Humoral Adaptive Immune System - Immunology
7. B-Lymphocyte Antigens - The Humoral Adaptive Immune System - Immunology
8. Basic Structure of Antibody Molecule - Immunology
9. Clonal Selection and Expansion - Immunology
10. Humoral Immune Effector Functions - Immunology
11. Opsonization of Antigen - Immunology
12. Mucosal Immunity - Immunology
13. Antibody-Dependent Cell Cytotoxicity (ADCC) - Immunology
14. Immediate Hypersensitivity - Immunology
15. Neonatal Immunity - Immunology
16. Activation of the Classical Complement Pathway - Immunology
17. Cell-Mediated Adaptive Immune System - Immunology
18. T-Lymphocyte Antigen Recognition and MHC Proteins - Immunology
19. Processing of Proteins to Allow Peptide Presentation by MHC Molecules - Immunology
20. More on T-Lymphocyte Subpopulations - Immunology
21. Effector T-Helper Cell Subtypes - Immunology
22. Transplantation Rejection - Clinical Perspective - Immunology
23. Hypersensitivity - Immunology
Chapter 10: Vaccination And Immunization
1. Vaccination and Immunization - Microbiology
2. Spread of Infection - Vaccination and Immunization
3. Objectives of A Vaccine/Immunization Programme - Microbiology
4. Classes of immunity - Passive (Artificially Acquired), Active (Artificially Acquired) Immunity
5. Passive (Artificially Acquired) Immunity - Types of immunity
6. Active (Artificially Acquired) Immunity - Types of immunity
7. Types of Vaccine - Vaccination
8. Live Vaccines - Types of Vaccine
9. Killed and Component Vaccines - Types of Vaccine
10. DNA Vaccines - Types of Vaccine
11. Poliomyelitis Vaccination - Routine Immunization Against Infectious Disease
12. Measles, Mumps And Rubella Vaccination (MMR) - Vaccination
13. Tuberculosis - Vaccination and Immunization
14. Diphtheria, Tetanus and A Cellular Pertussis (DTaP) Immunization - Immunization
15. Immunization against Bacteria Associated with Meningitis - Immunization
16. Human Papillomavirus (HPV) Vaccination - Vaccination
17. The UK Routine Childhood Immunization Programme - Immunization
18. Immunization of Special Risk Groups - Immunization
Part 3 - Prescribing therapeutics
Chapter 11: Antibiotics And Synthetic Antimicrobial Agents: Their Properties And Uses
1. Antibiotic Development, Past and Present - Microbiology
2. Antibiotic Usage - Microbiology
3. β -Lactam Antibiotics - Microbiology
4. Penicillins - Antibiotics and Synthetic Antimicrobial Agents
5. Cephalosporins - Antibiotics and Synthetic Antimicrobial Agents
6. β-Lactamase inhibitors - Antibiotics and Synthetic Antimicrobial Agents
7. Carbapenems and aztreonam - Antibiotics and Synthetic Antimicrobial Agents
8. Hypersensitivity - Antibiotics and Synthetic Antimicrobial Agents
9. Tetracyclines - Antibiotics and Synthetic Antimicrobial Agents
10. Macrolides - Antibiotics and Synthetic Antimicrobial Agents
11. Sulphonamides, Trimethoprim and Related Drugs - Antibiotics and Synthetic Antimicrobial Agents
12. Quinolones - Antibiotics and Synthetic Antimicrobial Agents
13. Aminoglycosides - Antibiotics and Synthetic Antimicrobial Agents
14. Glycopeptides - Antibiotics and Synthetic Antimicrobial Agents
15. Antitubercular Antibiotics - Antibiotics and Synthetic Antimicrobial Agents
16. Newer antibiotics for MRSA and other Gram - positive cocci infections - Antibiotics
17. Miscellaneous Antibacterial Antibiotics - Antibiotics
18. Antifungal Antibiotics - Antibiotics
19. Antiviral Drugs - Antibiotics
Chapter 12: Mechanisms of action of antibiotics and synthetic anti-infective agents
1. Introduction - Mechanisms of action of antibiotics and synthetic anti-infective agents - Microbiology
2. Peptidoglycan biosynthesis in bacteria and its inhibition - Mechanisms of action of antibiotics
3. β-Lactams-penicillins, cephalosporins, carbapenems and monobactams - Mechanisms of action of antibiotics
4. β-Lactamase Inhibitors-Clavulanic Acid, Sulbactam and Tazobactam - Mechanisms of action of antibiotics
5. Mycolic Acid and Arabinogalactan Biosynthesis in Mycobacteria - Microbiology
6. Echinocandins-Caspofungin, Anidulafungin and Micafungin - Microbiology
7. Protein synthesis and its selective inhibition - Microbiology
8. Chromosome Function and Replication - Basis for the Selective Inhibition of Chromosome Replication and Function - Microbiology
9. Fluoroquinolones - Chromosome Function and Replication
10. Rifampicin and Rifabutin - Chromosome Function and Replication
11. 5- Fluorocytosine - Chromosome Function and Replication
12. Folate Antagonists - Microbiology
13. The Cytoplasmic Membrane - Mechanisms of action of antibiotics and synthetic anti-infective agents - Microbiology
Chapter 13: Bacterial Resistance To Antibiotics
1. Bacterial Resistance to Antibiotics - Introduction - Microbiology
2. Origins of Resistance - Bacterial Resistance to Antibiotics
3. Mechanisms of Resistance - Bacterial Resistance to Antibiotics
4. Resistance to β-lactam antibiotics - Bacterial Resistance to Antibiotics
5. Altered Penicillin-Binding Proteins and Meticillin-Resistant Staphylococcus aureus - Bacterial Resistance to Antibiotics
6. Resistance to Glycopeptide Antibiotics - Bacterial Resistance to Antibiotics
7. Resistance to Aminoglycoside Antibiotics - Microbiology
8. Resistance To Other Antibiotics - Resistance To Tetracycline Antibiotics, Resistance To Antimycobacterial Therapy, Resistance To Peptide Antibiotics—Polymyxin, Resistance To Trimethoprim
9. Multiple Drug Resistance - Bacterial Resistance to Antibiotics
10. Clinical Resistance-Mic Values, Breakpoints, Phenotype and Outcome - Bacterial Resistance to Antibiotics
Chapter 14: Clinical Uses Of Antimicrobial Drugs
1. Clinical Uses of Antimicrobial Drugs - Introduction - Microbiology
2. Principles of Use of Antimicrobial Drugs - Microbiology
3. Clinical Uses of Antimicrobial Drugs - Microbiology
4. Respiratory Tract Infections - Clinical Uses of Antimicrobial Drugs
5. Urinary Tract Infections - Clinical Uses of Antimicrobial Drugs
6. Gastrointestinal Infections - Clinical Uses of Antimicrobial Drugs
7. Skin and Soft Tissue Infections - Clinical Uses of Antimicrobial Drugs
8. Central Nervous System Infections - Clinical Uses of Antimicrobial Drugs
9. Fungal Infections - Clinical Uses of Antimicrobial Drugs
10. Medical Device Associated Infections - Clinical Uses of Antimicrobial Drugs
11. Antibiotic Policies - Clinical Uses of Antimicrobial Drugs
12. The Antimicrobial Stewardship Team - Clinical Uses of Antimicrobial Drugs
Chapter 15: Antibiotic Prescribing And Antibiotic Stewardship
1. The Need for Antimicrobial Stewardship - Microbiology
2. Components of Antimicrobial Stewardship Programmes - Microbiology
3. The Effectiveness of Stewardship Strategies - Microbiology
4. Monitoring of Antibiotic Resistance - Antibiotic Prescribing and Antibiotic Stewardship
5. The Impact on Resistance of Antibiotic Availability to the Public - Antibiotic Prescribing and Antibiotic Stewardship
Chapter 16: Public Health Microbiology: Infection Prevention And Control
1. Public Health Microbiology: Infection Prevention and Control - Microbiology
2. Healthcare-Associated Infections-Definitions and Range - Microbiology
3. Microorganisms that Cause HCAI - Infection Prevention and Control
4. Scale of the HCAI Problem-Prevalence and Incidence - Infection Prevention and Control
5. Responsibility for HCAI Prevention and Control - Infection Prevention and Control
6. Keys to Infection Prevention and Control - Infection Prevention and Control
7. Zero Tolerance and the Principles of Infection Management - Infection Prevention and Control
8. Professional Support for Infection Prevention and Control - Public Health Microbiology
Part 4 - Contamination and infection control
Chapter 17: Microbial Spoilage, Infection Risk And Contamination Control
1. Microbial Spoilage, Infection Risk and Contamination Control - Introduction
2. Spoilage-Chemical and Physicochemical Deterioration of Pharmaceuticals - Microbial Spoilage
3. Pharmaceutical Ingredients Susceptible to Microbial Attack - Microbial Spoilage
4. Observable Effects of Microbial Attack on Pharmaceutical Products - Microbial Spoilage
5. Factors Affecting Microbial Spoilage of Pharmaceutical Products - Microbiology
6. Hazard to Health - Microbial Spoilage
7. Sources and Control of Contamination - Microbial Spoilage
8. The Extent of Microbial Contamination - Microbial Spoilage
9. Factors Determining the outcome of a Medicament-Borne Infection - Microbial Spoilage
10. Preservation of Medicines Using Antimicrobial Agents: Basic Principles - Microbial Spoilage
11. Effect of Preservative Concentration, Temperature and Size of Inoculum - Microbial Spoilage
12. Factors Affecting The ‘Availability’ of Preservatives - Microbial Spoilage
13. Quality Assurance and the Control of Microbial Risk in Medicines - Microbial Spoilage
14. Quality Assurance in Formulation Design and Development - Microbial Spoilage
15. Good Pharmaceutical Manufacturing Practice (GPMP) - Microbial Spoilage
16. Quality Control Procedures - Microbial Spoilage
17. Postmarket Surveillance - Microbial Spoilage
Chapter 18: Laboratory Evaluation Of Antimicrobial Agents
1. Laboratory Evaluation of Antimicrobial Agents - Microbiology
2. Definitions - Laboratory Evaluation of Antimicrobial Agents
3. Factors Affecting the Antimicrobial Activity of Disinfectants - Microbiology
4. Evaluation of Liquid Disinfectants - Laboratory Evaluation of Antimicrobial Agents
5. Evaluation of Solid Disinfectants - Laboratory Evaluation of Antimicrobial Agents
6. Evaluation of Air Disinfectants - Laboratory Evaluation of Antimicrobial Agents
7. Evaluation of Preservatives - Laboratory Evaluation of Antimicrobial Agents
8. Rapid Evaluation Procedures - Laboratory Evaluation of Antimicrobial Agents
9. Evaluation of Potential Chemotherapeutic Antimicrobials - Laboratory Evaluation of Antimicrobial Agents
10. Tests for Biofilm Susceptibility - Laboratory Evaluation of Antimicrobial Agents
Chapter 19: Chemical Disinfectants, Antiseptics And Preservatives
1. Chemical Disinfectants, Antiseptics and Preservatives - Microbiology
2. European Union Regulation for Chemical Disinfectants, Antiseptics and Preservatives - Microbiology
3. Definitions - Chemical Disinfectants, Antiseptics And Preservatives - Definitions - Chemical Disinfectants, Antiseptics And Preservatives, Disinfectant And Disinfection, Microbiology, Antiseptic And Antisepsis, Preservative And Preservation
4. Economic Aspects - Chemical Disinfectants, Antiseptics and Preservatives - Microbiology
5. Factors Affecting Choice of Antimicrobial Agent - Microbiology
6. Types of Compound - Chemical Disinfectants, Antiseptics and Preservatives
7. Disinfection Policies - Chemical Disinfectants, Antiseptics and Preservatives
Chapter 20: Non-Antibiotic Antimicrobial Agents: Mode Of Action And Resistance
1. Non-Antibiotic Antimicrobial Agents: Mode of Action and Resistance - Microbiology
2. Mechanisms of Action - Non-Antibiotic Antimicrobial Agents
3. Enhancing Activity of Non-Antibiotic Antimicrobial Agents - Microbiology
4. Mechanisms of Resistance to Biocides - Non-Antibiotic Antimicrobial Agents
5. Viricidal Activity of Biocides - Non-Antibiotic Antimicrobial Agents
6. Biocides and Protozoa - Non-Antibiotic Antimicrobial Agents
7. Biocides and Fungi - Non-Antibiotic Antimicrobial Agents
8. Inactivation of Prions - Non-Antibiotic Antimicrobial Agents
Chapter 21: Sterilization Procedures And Sterility Assurance
1. Introduction - Sterilization Procedures and Sterility Assurance | Microbiology
2. Sensitivity of Microorganisms - Sterilization Procedures and Sterility Assurance | Microbiology
3. Sterilization Methods - Sterilization Procedures and Sterility Assurance | Microbiology
4. Heat Sterilization - Sterilization Methods - Sterilization Procedures and Sterility Assurance | Microbiology
5. Gaseous Sterilization - Sterilization Methods - Sterilization Procedures and Sterility Assurance | Microbiology
6. Radiation Sterilization - Sterilization Methods - Sterilization Procedures and Sterility Assurance | Microbiology
7. Filtration Sterilization - Sterilization Methods - Sterilization Procedures and Sterility Assurance | Microbiology
8. New Sterilization Technologies - Sterilization Procedures and Sterility Assurance | Microbiology
9. Sterilization Control and Sterility - Sterilization Procedures and Sterility Assurance | Microbiology
10. Bioburden Determinations - Sterilization Procedures and Sterility Assurance | Microbiology
11. Environmental Monitoring - Sterilization Procedures and Sterility Assurance | Microbiology
12. Validation and In-Process Monitoring of Sterilization Procedures - Sterilization Procedures and Sterility Assurance | Microbiology
13. Sterility Testing - Sterilization Procedures and Sterility Assurance | Microbiology
Part 5 - Pharmaceutical production
Chapter 22: Sterile Pharmaceutical Products
1. Introduction - Sterile Pharmaceutical Products
2. Types of Sterile Product - Sterile Pharmaceutical Products
3. Injections - Types of Sterile Product
4. Non-Injectable Sterile Fluids - Types of Sterile Product
5. Ophthalmic Preparations - Types of Sterile Product
6. Dressings - Types of Sterile Product
7. Implants - Sterile Pharmaceutical Products
8. Absorbable Haemostats - Types of Sterile Product
9. Surgical Ligatures and Sutures - Sterile Pharmaceutical Products
10. Instruments and Equipments - Sterile Pharmaceutical Products
11. Sterilization Considerations - Sterile Pharmaceutical Products
12. Quality Control and Quality Assurance - Sterile Pharmaceutical Products
Chapter 23: Principles Of Good Manufacturing Practice
1. Principles of Good Manufacturing Practice - Pharmaceutical Microbiology
2. Definitions - Principles of Good Manufacturing Practice | Pharmaceutical Microbiology
3. Control of Microbial Contamination During Manufacture: General Aspects - Principles of Good Manufacturing Practice | Pharmaceutical Microbiology
4. Manufacture of Sterile Products - Pharmaceutical Microbiology
5. Aseptic Areas - Principles of Good Manufacturing Practice | Pharmaceutical Microbiology
6. Guide to Good Pharmaceutical Manufacturing Practice - Principles of Good Manufacturing Practice | Pharmaceutical Microbiology
Chapter 24: The Manufacture And Quality Control Of Immunological Products
1. The Manufacture and Quality Control of Immunological Products - Pharmaceutical Microbiology
2. Vaccines, Types of Vaccines - Pharmaceutical Microbiology
3. The Seed Lot System - Immunological Products | Pharmaceutical Microbiology
4. Production of the Bacteria and the Cellular Components of Bacterial Vaccines - Pharmaceutical Microbiology
5. Fermentation - Pharmaceutical Microbiology
6. Production of the Viruses and the Components of Viral Vaccines - Pharmaceutical Microbiology
7. Blending - Immunological Products | Pharmaceutical Microbiology
8. Filling and Drying - Immunological Products | Pharmaceutical Microbiology
9. Quality Control - Immunological Products | Pharmaceutical Microbiology
10. In Vivo Diagnostics - Immunological Products | Pharmaceutical Microbiology
11. Immune Sera - Immunological Products | Pharmaceutical Microbiology
12. Human Immunoglobulins - Immunological Products | Pharmaceutical Microbiology
13. Monoclonal Antibodies - Immunological Products | Pharmaceutical Microbiology
Chapter 25: Recombinant DNA Technology
1. Biotechnology in Pharmaceutical Sciences - Recombinant DNA Technology
2. Enabling Techniques - Recombinant DNA Technology
3. Cutting and Joining DNA Molecules - Enabling Techniques - Recombinant DNA Technology
4. Cloning Vectors - Enabling Techniques - Recombinant DNA Technology
5. Introduction of Vector Into Hosts - Recombinant DNA Technology
6. Construction of Genomic Libraries - Recombinant DNA Technology
7. Screening of Genomic Libraries - Recombinant DNA Technology
8. Optimizing Expression of Recombinant Genes - Recombinant DNA Technology
9. Amplifying DNA: The Polymerase Chain Reaction - Recombinant DNA Technology
10. Biotechnology in the Pharmaceutical Industry - Recombinant DNA Technology
11. Recombinant Human Insulin - Recombinant DNA Technology
12. Recombinant Somatostatin - Recombinant DNA Technology
13. Recombinant Somatotropin - Recombinant DNA Technology
14. Recombinant Hepatitis B Vaccine - Recombinant DNA Technology
15. Recombinant Influenza Virus Vaccines - Recombinant DNA Technology
16. Production of Recombinant Antibiotics - Recombinant DNA Technology
17. New Diagnostics Using Recombinant DNA Technology - Recombinant DNA Technology
18. Diagnosis of Infectious Diseases - Recombinant DNA Technology
19. Diagnosis of Genetic Disorders - Recombinant DNA Technology
Part 6 - Current trends and new directions
Chapter 26: The Wider Contribution Of Microbiology To The Pharmaceutical Sciences
1. The Wider Contribution of Microbiology to the Pharmaceutical Sciences - Pharmaceutical Microbiology
2. Pharmaceuticals Produced by Microorganisms - Wider Contribution of Microbiology to the Pharmaceutical Sciences
3. Iron-Chelating Agents - Wider Contribution of Microbiology to the Pharmaceutical Sciences
4. Enzymes - Wider Contribution of Microbiology to the Pharmaceutical Sciences
5. Applications of Microorganisms in the Partial Synthesis of Pharmaceuticals - Pharmaceutical Microbiology
6. Applications of Microorganisms in the Discovery of Pharmaceuticals - Pharmaceutical Microbiology
7. Use of Microorganisms and their Products in Assays - Pharmaceutical Microbiology
8. Phenylketonuria Testing - Pharmaceutical Microbiology
9. Carcinogen and Mutagen Testing - Wider Contribution of Microbiology to the Pharmaceutical Sciences
10. Use of Microbial Enzymes in Sterility Testing - Pharmaceutical Microbiology
11. Immobilized Enzyme Technology - Wider Contribution of Microbiology to the Pharmaceutical Sciences
12. Use of Microorganisms as Models of Mammalian Drug Metabolism - Pharmaceutical Microbiology
13. Microorganisms as Therapy - Pharmaceutical Microbiology
14. Insecticides - Pharmaceutical Microbiology
15. Bioterrorism - Wider Contribution of Microbiology to the Pharmaceutical Sciences
16. Bioterrorism - Wider Contribution of Microbiology to the Pharmaceutical Sciences
Chapter 27: Alternative Strategies For Antimicrobial Therapy
1. Alternative Strategies for Antimicrobial Therapy - Pharmaceutical Microbiology
2. Essential Oils - Alternative Strategies for Antimicrobial Therapy
3. Honey Therapy - Alternative Strategies for Antimicrobial Therapy
4. Garlic - Alternative Strategies for Antimicrobial Therapy
5. Probiotics - Alternative Strategies for Antimicrobial Therapy
6. Maggot Therapy - Alternative Strategies for Antimicrobial Therapy
7. Photodynamic Therapy (Photoactivated Disinfection) - Alternative Strategies for Antimicrobial Therapy
8. Vaccines and Immunotherapies - Alternative Strategies for Antimicrobial Therapy
9. Silver - Alternative Strategies for Antimicrobial Therapy
10. Bacteriophage Therapy - Alternative Strategies for Antimicrobial Therapy
11. Bacteriophage Lysins - Alternative Strategies for Antimicrobial Therapy
Comments
Post a Comment